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The reoxygenation of tissue that has been deprived of adequate oxygen (ischaemia) as a result of either surgical procedures or physiological dysfunction. Vital organs can tolerate only a brief period of oxygen deprivation before cell injury and death occur. Subsequent reperfusion, however, can also cause tissue damage. Ischaemia reperfusion damage can be prevented or decreased in the presence of antioxidants.

Source: Biotechnology Glossary